Too early to trim?

40 days in and some of these leaves are getting big wondering when is the best time to clip some off

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Ifnur still in veg if photos ur good to defol now if want. Wait a week then flip to flower. But usually afyer flower flip its 21 days 42 days and 2 weeks before chop. Veg can defol anytime as lo g as u dont overdue it. Welcome and good luck. I do massive defols to my plants when i do them

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