Just monitor air flow and humidity. Air flow will be cut down so find a way to boost it and with increased foilage in a tight spot rh should boost so find a way to drop it when you need to. Other then that you should be fine.
I saw it touched on up there…
If they grow as big as your thinking, you’ll be slightly under powered for lighting I think. That’s the one thing I’d always rather have too much of.
Skilled growers with good lighting pull 1lb harvests from 3x3.
Good luck, they’re coming along awesome.
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